So, Ponatinib is this special BCR-ABL inhibitor that’s used for treating CML, especially in adults who have this T315I mutation or didn’t respond to earlier TKIs. And it’s also used for a type of ALL called Ph ALL, especially in kids and adults who couldn’t handle earlier TKIs. Even if they have that T315I thing going on.
Ponatinib’s a multi-kinase inhibitor—it hits on a bunch of kinases, which are these fancy words for parts of cells that help cancer cells keep growing and surviving. The tablets come in two strengths: 15 mg or 45 mg. They usually suggest taking 45 mg of it every day, whether you’ve had your meal or not.
The tablets come in bottles, each with 30 of the film-coated variety.
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