So, neratinib is this super strong HER2 inhibitor that’s used to treat breast cancer where HER2 is involved. It stops those EGFR/HER2 pathways in their tracks. It comes in tablet form, and each one is 40 milligrams.
You’re supposed to take 240 milligrams of it every day, and it’s best to take it with food. You’ve got to take the pill either an hour before or two hours after eating so it can be absorbed right. Each bottle holds 180 of these tablets.
Neratinib’s main job is to help with breast cancer that’s spread, especially after you’ve already had trastuzumab and a taxane, or if you can’t take those drugs. There are some side effects like diarrhea, rashes, nausea, and feeling like you don’t want to eat. You might need to keep an eye on your liver and bone marrow while you’re on this stuff.
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