This drug, larotrectinib, is a TRK inhibitor, which means it’s used to treat solid tumors that have a specific NTRK gene fusion. It’s designed to attach to, and block, TRKA, TRKB, and TRKC, which are protein receptors responsible for tumor growth. Indicated for adults and pediatric patients with unresectable or metastatic NTRK-fusion-positive cancer, You can get larotrectinib in two types of capsules – 25 mg or 100 mg, or as a 20 mg/mL solution, just to make taking it easier.
The usual dose for grown-ups is 100 mg, taken in the morning and night. As for kids, you figure out the dosage based on their surface area, so everyone gets the right amount.
