This inhibitor, Crizotinib, is used to treat a type of lung cancer called NSCLC, especially when there’s an ALK or ROS1 mutation. It’s a tyrosine kinase inhibitor, which stops certain enzymes that help cancer cells grow and live. There are two doses for this drug: 200 mg and 250 mg.
Usually, people take the 250 mg version, twice a day, with or without eating. It comes in bottles with 60 capsules each. Crizotinib goes after not just ALK and ROS1, but also MET kinases.
This makes it super effective at stopping more than one thing in cancer cells. Doctors usually start patients on 200 mg twice a day and might go up to the 250 mg dose if they handle it okay and it seems to be working.
