So, Elacestrant is this drug used for ER /HER2 breast cancer. It breaks down the ER signaling thing. You can get it in 86 mg or 345 mg doses.
The go-to dose is 345 mg, and you should take it with food every day. The tablets are all coated, no worries about them being chewed. The stuff comes in bottles with 30 tablets in each.
Elacestrant works by going after the estrogen receptors, which are kind of like troublemakers in breast cancer cells. They’re like the life support system for cancer cells. So, it latches onto these receptors, keeping estrogen from doing its evil work, which in turn slows down the cancer growth.
SERDs are drugs that hook onto these receptors without getting them excited, causing them to kind of fall apart. And this breakdown leads to the receptors getting yanked away from the cell surface, so they can’t send those bad messages inside. This strategy is a big deal for breast cancer since is like a motor running the whole show.
