Gilteritinib is an FLT3 inhibitor. It’s used to treat AML that’s come back or doesn’t respond to treatment, especially in cases with FLT3 mutations. It works by blocking FLT3 kinase, which helps slow down the growth of leukemia cells.
You can get the drug in 40 mg tablets with a film coating. The usual dose is 120 mg, taken by mouth every day. Gilteritinib comes in bottles that hold 90 tablets.
It’s a small molecule that targets the FLT3 receptor on cancer cells. This receptor is really important for AML to grow and spread in people with FLT3 mutations. The tablets are made to be easy to take, and you can take them with or without eating.
Gilteritinib blocks the signaling pathway that gets turned on too much because of FLT3. This stops cancer cells from growing and makes them die.
