Mitotane is a drug used to treat adrenocortical carcinoma. It works by keeping the adrenal glands from doing their thing. You can get it in 500 mg pills.
You usually start with 2 to 6 grams a day, split up, and the amount can change depending on how your body handles it. Each bottle has 100 tablets, which should last about a month if you’re taking it as prescribed. Mitotane works by blocking cortisol from sticking to the adrenal glands and stops them from making steroids like aldosterone and cortisol.
It’s also good at stopping hormones from coming back for people who’ve had surgery or radiation. They usually check how well Mitotane is working by looking at how much it reduces the 11-deoxycortisol/cortisol ratio after just one dose. You gotta weigh the pros and cons, because it can cause some issues like liver problems, feeling queasy, not wanting to eat, and throwing up.
Mitotane is like a generic drug because it’s pretty easy to get and it’s cheaper than the name brands.
