So, Neratinib is this thing called an irreversible HER2 inhibitor. It’s mainly used to treat breast cancer that has this HER2-positive thing going on. It works by blocking this whole EGFR/HER2 signaling pathway.
The formulation comes in these tablets that have a coating. They’re strong, like 40 mg each. The usual dosage is 240 mg, and you take it once a day with your meals.
You get these tablets in bottles, with 180 pills in each one. Neratinib is like a hunter for the HER2 overexpression in breast cancer cells. It helps keep the cancer from growing and spreading.