Pemigatinib is an inhibitor that specifically zeroes in on cholangiocarcinomas with FGFR2 fusions. It blocks FGFR signaling. There are three strengths: 4.5 mg, 9 mg, and 13.5 mg.
You’re supposed to take the 13.5 mg pill once a day. You’ll have a 21-day cycle where you take the medicine for 14 days straight, then take a 7-day break. Each bottle contains 14 tablets.
You’ve got to take your dose for 14 days in a row every 21-day cycle. It’s real important to follow the dosing and cycle instructions to keep it working and to minimize side effects.